Physical activity across the cancer continuum.

Research on the potential influence of physical activity on cancer outcomes is extensive, and it encompasses basic science; animal models; large-scale prospective epidemiologic research; and randomized controlled trials of a wide range of physical activity interventions designed to improve quality of life, functional status, and a number of physiologic parameters that may influence cancer risk and recurrence. In this issue of ONCOLOGY, the review by Lemanne et al provides selected highlights of this field of research. In our commentary, we will address ways to consider this research across the cancer continuum, with a focus on the cancer survivor, highlighting some of the challenges in interpreting the research evidence for translation into clinical practice and noting some research gaps.